On Gizzie, the relationship between her Grey’s character Izzie and George (T.R. Knight): “That was kind of a big change for Izzie, wasn’t it, after she was so up on her moral high ground. They really hurt somebody, and they didn’t seem to be taking a lot of responsibility for it. I have a really hard time with that kind of thing. I’m maybe a little too black-and-white about it. I don’t really know Izzie very well right now. She’s changed a lot. I’m trying to figure her out and keep her real… It was a ratings ploy. It was absolutely something that shocked people; it wasn’t predictable, and people didn’t see it coming. It’s our fourth season; there’s not a lot of spontaneity left. And business is business; I understand that, but I want there to be some cooperation between the business end and the creative end, so there’s some way of keeping it real.”